If your pup's liver becomes inflamed for longer than six weeks the condition is referred to as chronic hepatitis. In today's post our Greenboro vets share more about the causes and symptoms of canine chronic hepatitis in dogs.

What is hepatitis in dogs?

Hepatitis in dogs is classified into two categories:

Infectious Canine Hepatitis

Infectious canine hepatitis is an acute contagious disease caused by the canine adenovirus 1. This virus targets the spleen, kidneys, lungs, liver, lining of blood vessels and sometimes other organs. Symptoms can vary widely - from slight fever, thirst or apathy to death.

Canine Chronic Hepatitis

Canine chronic hepatitis is associated with infectious canine hepatitis. At some point, the dog's liver has become inflamed and necrosis (cell death) has occurred.

Dog breeds that seem to face an increased risk of developing this disease include Chihuahuas, Springer Spaniels, Beagles, Maltese, West Highland White Terriers, Cocker Spaniels, Labrador Retrievers, Bedlington Terriers, Skye Terriers, Doberman Pinschers, and Standard Poodles.

In some breeds, an accumulation of copper in the liver’s cells can result in chronic hepatitis. An excessive amount of copper can damage the liver’s cells and often leads to severe chronic hepatitis if left untreated.

Chronic means the infection has been damaging cells for some time (at least a few weeks). While acute hepatitis can manifest over just a few days.

Symptoms of Chronic Hepatitis in Dogs

Symptoms of chronic canine hepatitis can include:

Sluggishness and lethargy
Lack of appetite
Weight loss
Vomiting
Seizures, mental dullness

Increased urination
Excessive thirst
Yellowish gums and moist tissues
Abdominal fluid buildup
Poor body condition

Causes of Chronic Hepatitis in Dogs

Dogs can develop chronic hepatitis due to a number of causes including:

Exposure to toxins
Infectious disease
Immune-mediated disease
Copper-storage disease
Environmental
Drug related

Diagnosis of Chronic Hepatitis in Dogs

To begin, your vet will request a detailed history of your dog's health leading up to the onset of symptoms. Any information you can provide your veterinarian about your dog's genetic background and parentage will also be helpful.

Your vet will complete a thorough physical examination on your dog, including a blood chemical profile, a complete blood count (CBC), an electrolyte panel and a urinalysis. The bloodwork results will allow your veterinarian to look for indications of impaired kidney function.

In some cases, your vet may use X-ray and ultrasound imaging to visually examine the liver, or take a tissue sample for biopsy.

Treating Chronic Hepatitis in Dogs

Hospitalization will be necessary in severe cases so that your pup can be given fluid therapy supplemented with B vitamins, potassium and dextrose.

Restricted activity will also be necessary during the treatment and recovery phase. Your vet may or may not recommend complete cage rest depending on your dog's specific case. Be sure to keep your dog warm while they are inactive during their recovery period.

Medications may be prescribed by your vet to increase the elimination of fluids from the body, helping to decrease fluid build-up in the abdomen. Medications may also be necessary to treat infection, decrease brain swelling, control seizures, and decrease ammonia production and absorption.

A diet restricted in sodium, and supplemented with thiamine and vitamins should be served to your dog in several small meals a day (avoid 2 or 3 large meals). If your dog has lost their appetite and refuses to eat for more than 48 hours an intravenous feeding tube may be necessary to get your pet the nutrition they need to prevent further muscle wasting.